Bloomsdale is a city in Ste. Genevieve County, Missouri, United States. The population was 639 at the 2020 census. The name of the town i…Bloomsdale is a city in Ste. Genevieve County, Missouri, United States. The population was 639 at the 2020 census. The name of the town is most likely derived from the name of a Catholic priest, Father Blume.