The Detroit Lions opened their 2025 preseason in Canton, Ohio against a fellow 2024-25 playoff team, the Los Angeles Chargers, on Thursday night with the Chargers winning a 34-7 game. The game included a rough performance from the Lions' offense as Detroit was outgained 267 yards to 197 against Jim Harbaugh's team.

T he Lions appeared to escape the first and "extra" preseason game with only minor injuries. The main concern going forward may be whether Hendon Hooker suffered another preseason concussion. Skipper suffered a self-reported (via Justin Rogers),

There was a moment of silence before the game as Commissioner Roger Goodell paid tribute to the lives lost during a shooting in the NYC building that houses the NFL headquarters earlier this week.