For cancer cells to metastasize, they must first penetrate a dense sheet-like mesh of proteins and other molecules called the basement membrane, which surrounds tissues like a Kevlar wrapper. But very ...

Too much of this enzyme, matrix metalloproteinase 2 (MMP2), might be causing the disturbance to the basement membrane. An experiment using model mice with vitiligo-like depigmentation showed ...

Carbonell, W. S., Ansorge, O., Sibson, N. & Muschel, R. The vascular basement membrane as “soil” in brain metastasis. PLoS One 4, e5857 (2009). An assumption ...

The newer, wilder cells created by another mutation are able to push their way through the epithelial tissue's basement membrane, which is a meshwork of protein that normally creates a barrier.

Multilayering of the basement membranes of peritubular capillaries (MLPTC) observed on electron microscopy is a feature of chronic kidney allograft rejection. Biopsy specimens with MLPTC have also ...