For example, researchers will measure cell death to determine a drug’s anticancer effectiveness. Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark ...

are frequently used as apoptosis assays in vivo. Mitochondrial apoptotic signalling and mitochondrial outer-membrane permeabilization (MOMP) controlled by the B-cell lymphoma 2 (BCL-2) family of ...

In Ming-Chiu Fung’s immunology lab, Hogan had been investigating how disturbances in the cytoskeletons of cells might contribute to the fragmentation of mitochondria during apoptosis, the most ...

Ovarian cancer, a leading cause of death among gynecological malignancies, has a poor prognosis and low 5-year survival rate, necessitating new therapeutic strategies. CDK4/6 inhibitors show promise ...

Moreover, the researchers analyzed the effects of miR-377 on apoptosis, proliferation, cell cycle ... as confirmed by luciferase assay and Real-time PCR. They observed a significant reduction ...

This study aimed to elucidate the molecular mechanism of TNIP1 regulation in the proliferation and apoptosis of breast cancer cells. A colony formation assay was conducted on MCF-7 and T47D cells ...