Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Selectively inactivating a molecular switch that turns on the gene Nr4a1 in monocytes but not macrophages leads to the loss of patrolling monocytes, which play an important role in suppressing ...

The monocyte effect. Monocytes/macrophages (promonocytes in the bone marrow, circulating monocytes, tissue macrophages) play a major role in the induction and regulation of immune reactivity.

More information: Alexander Simonis et al, Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages, Molecular Systems Biology (2025). DOI: 10.1038/s44320-025 ...

In this application note, explore how scientists can couple a serum-free medium with a xeno-free serum replacement to effectively culture functional monocyte-derived dendritic cells and macrophages.

Macrophages eat other cells and are able to pull apart their ... J. E., and Munder, M. (2009) Monocyte dependent regulation of autoimmune inflammation.

The study 'Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages' led by Professor Dr Jan Rybniker, who heads the Division of Infectious Diseases at ...