Apoptosis is the process of controlled cellular “suicide”. Whereas in necrosis cells die due to injury or disease, apoptosis is a natural part of the regulation and development of the body’s ...

Apoptosis — the regulated destruction of a cell — is a complicated process. The decision to die cannot be taken lightly, and the activity of many genes influence a cell's likelihood of ...

Caspase-1 initiates apoptosis, but not pyroptosis, in the absence of gasdermin D. Kanazawa University. Journal Nature Communications Funder Grants-in-Aid (KAKENHI), Japan Society for the Promotion ...

Forms of this process have also been documented in single-celled eukaryotes like yeast. Scientists have long wondered about the origins of this process. New research has found that the apoptosis may ...

Apoptosis, sometimes called "cellular suicide," is a normal, programmed process of cellular self-destruction. Even though it involves cell death, apoptosis serves a healthy and protective role in ...

There are many different triggers of apoptosis, but they all ultimately activate executioners called caspases. Cleaving hundreds of different kinds of proteins within a cell, these enzymes wreak havoc ...

In the process of apoptosis, the group of proteases called caspases, about 10 species of which are found in humans, function as suicide enzymes. Caspase-1, ...

Apoptosis. Apoptosis is a process mediated by caspases that is essential for removing damaged or unwanted cells. During apoptosis, cell membranes shrink, chromatin agglutinates, ...