How to treat a shingles rash at home As for treating shingles symptoms at home, over-the-counter pain relievers, like acetaminophen or ibuprofen can also help ease the discomfort, Dr. Dasgupta says.

Some people with shingles only experience mild symptoms. They may develop a rash, fatigue, headaches, and a low grade fever. Home remedies and over-the-counter (OTC) treatments may help relieve ...