Local Rule-Based Theory of Virus Shell Assembly. Proceedings of the National Academy of Sciences of the United States of America, 1994. 91(16): p. 7732-7736. Elrad, O. M. and M.F. Hagan, Mechanisms of ...

The dengue virus has a roughly spherical shape. Inside the virus is the nucleocapsid ... It is composed of the viral genome and capsid proteins surrounded by an envelope and a shell of proteins.

For many years, scientists have explored the structural changes of the virus capsid which encases the genome. In contrast, much less is known about the virus matrix—the outer protein shell ...

Gilead Sciences announced a significant milestone: the U.S. FDA accepted their New Drug Applications (NDAs) for lenacapavir ...

The 3.0 Å resolution crystal structure of Pariacoto virus (PaV) reveals extensive interactions between portions of the viral RNA genome and the icosahedral capsid ... in both shape and ...

AI-assisted adeno-associated virus (AAV) capsid engineering has transformative potential in terms of accelerating and optimizing the development of gene therapies. That’s the view of Fangzhi Tan ...

This involves the HIV-1 protease (a viral enzyme), that cuts up Gag into six smaller proteins including the capsid protein and the matrix protein. This causes a huge structural rearrangement of the ...