Turning X chromosome 'off and on again' critical for oocyte development Discovery of 'yoyo' mechanism could pave the way for generating artificial oocytes in the lab Date: May 23, 2022 Source ...

Oocyte quality is the key limiting factor of female fertility. However, compared with other species, the research and understanding of human oocyte quality and human reproductive health is limited.

The causes of embryonic arrest during pre-implantation development are poorly understood. Attempts to correlate patterns of oocyte gene expression with successful embryo development have been ...

The results showed infection with SARS-CoV-2 before oocyte retrieval has no clear negative effects on oocyte and embryo development. But there is still a need to watch out for viral infections ...

In 1998, James Thomson and co-workers became the first scientists to derive and successfully culture human embryonic stem cells (hES cells) from a human blastocyst, an early human embryo of ...

The findings suggest that right from the get-go of human egg cell development, a striking proportion of oocytes are predestined to be chromosomally abnormal.

The hallmark of successful human reproduction is the fusion between a haploid spermatozoon and a metaphase II oocyte. The generation of such an oocyte involves a series of steps whereby germinal-ve ...

Human oocytes can last for up to 50 years—and a newly discovered metabolic pathway is key to this longevity.

The results demonstrate that H3K4me3 is involved in stabilizing chromosomes and spindles, and is crucial for normal oocyte development and subsequent embryogenic potential.

Dioseve’s mission to grow human oocytes, or eggs, from other tissue is based on a scientific technique called induced pluripotent cells stem (iPS) cells ...

A new international study presented today at the 41st Annual Meeting of the European Society of Human Reproduction and ...