Background At least 60% of stroke, 40% of dementia and 35% of late-life depression (LLD) are attributable to modifiable risk ...

Background Previous natural history studies highlighted a consistent heterogeneity of disability trajectories among ...

Dr G Midroni, Neurophysiology laboratory, St. Michael’s Hospital, 30 Bond Street, Toronto, Ontario, Canada M5B 1W8. Telephone 00416 864 5193; fax 00416 864 6095. A 22 year old woman with recently ...

Background The link between low-density lipoprotein cholesterol (LDL-C) levels and dementia risk is poorly understood, with conflicting evidence on the role of LDL-C and the impact of statin therapy ...

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Apathy is increasingly recognised as a common behavioural syndrome in psychiatric disorders, but it is conceptually ill defined. The aim of this study was to examine the concept of apathy as it is ...

Correspondence to Dr Ruth Ann Marrie, Internal Medicine, University of Manitoba College of Medicine, Winnipeg, MB R3A 1R9, Canada; rmarrie{at}hsc.mb.ca Pain can be one of the worst symptoms of ...

Dr Paul T Francis, Dementia Research Laboratory, Division of Biomolecular Sciences, Guy’s, King’s and St Thomas’ Schools of Biomedical Sciences, King’s College, St Thomas Street, London SE1 9RT, UK.

Objective APOE is a strong risk factor for Alzheimer’s disease (AD) and associated with higher low-density lipoprotein cholesterol (LDL-C) levels. Moreover, LDL-C is associated with the development of ...

Objective Visual hallucinations are common in Parkinson’s disease (PD) and associated with worse outcomes. Large-scale network imbalance is seen in PD-associated hallucinations, but mechanisms remain ...

Background MRI-guided focused ultrasound (MRgFUS) thalamotomy is a promising non-invasive treatment option for medication-resistant essential tremor. However, it has been associated with variable ...