The serious side effects of phototherapy, such as overheating and dehydration, are driving the need for adjuvant therapies. A new literature review has observed promising results from the use of zinc ...

The most frequently mutated genes were associated with epigenetic regulatory mechanisms, namely TET2, ASXL1, and DNMT3A. Next-generation sequencing (NGS) identified 14 gene mutations with diagnostic ...

Researchers found that although primary intraosseous Rosai-Dorfman disease has histopathological features that overlap with IgG4-RD, it does not meet the criteria for IgG4-RD. Although primary ...

Castleman disease and IgG4-RD have overlapping disease manifestations that can complicate the diagnostic process. A male patient initially suspected of having immunoglobulin G4-related disease ...

Over 80% achieved a clinically meaningful improvement in at least one of the scales assessed. Treatment with risdiplam over 30 months led to overall clinically meaningful improvement in most adult ...

The prevalence of AATD in the offspring of parents with AATD in our study was 37%. A risk of pregnancy complications and adverse birth outcomes has been observed in mothers with alpha-1 antitrypsin ...

These estimates, despite certain limitations, offer a more accurate representation of the indolent SM burden and its comparison with other diseases. A recent study highlighted the significant burden ...

The relationship between RA and AAV—two autoimmune disorders—needs further exploration. Rheumatoid arthritis (RA) is found to often precede the diagnosis of antineutrophil cytoplasmic antibody ...

Conclusive histopathological evidence led to a diagnosis of IgG4-related retroperitoneal fibrosis in a patient with chronic abdominal pain. A young man with worsening abdominal pain radiating to his ...

Patients with ANCA-positive interstitial lung disease (ILD) exhibited a high prevalence of fibrotic patterns and mortality largely driven by the ILD itself. In patients with interstitial lung disease ...

Patients with CIDP had significantly lower levels of total N-glycans in their serum compared to healthy people. The levels of sialylated N-glycans in the serum could be a novel biomarker in chronic ...

The results suggest that rituximab could potentially serve as a first-line treatment for patients with acquired hemophilia A. Researchers have reported 2 cases of successful elimination of factor VIII ...