TypeScript 4.7 and 4.8 introduce ES Module (ESM) support for Node.js, improved type inference and control flow analysis, and significant performance improvements.

Type stripping allows Node.js developers to run TypeScript without source maps or additional configuration, speeding up the development process.

Deno is a rethink of a server-side JavaScript runtime from original Node.js creator Ryan Dahl, to address regrets and challenges with Node.js.

However, unlike Node.js, Deno offers first-class support for Microsoft's increasingly popular Typescript, a superset of JavaScript designed for large projects.