In March 2025, Shandong Suncadia Medicine Co., Ltd. conducted a phase II Clinical Study of Efficacy and Safety of HRS-1780 ...

Aldosterone is known to bind to these receptors in the kidney and cardiovascular system, increasing blood pressure through increasing sodium reabsorption and probably other mechanisms. The drug is ...

The human kidney displays a tubular immaturity at ... Sodium reabsorption is mainly controlled by aldosterone, a steroid hormone synthesized in the zona glomerulosa of the adrenal gland, secondary ...

Elevated aldosterone stimulates sodium reabsorption ... This specific protein facilitates the reabsorption of magnesium in the kidney tubules, resulting in low magnesium in the blood.

The adrenal glands are two small, roughly triangular glands that sit on top of the kidneys. They make steroid hormones (like ...

Addison’s disease is caused by damage to the adrenal glands — two small, triangular glands that sit above the kidneys and produce cortisol, aldosterone, and, to a lesser degree, sex steroids.

BofA Securities, Evercore ISI, Goldman Sachs & Co. LLC, Stifel and Wells Fargo Securities are acting as joint book-running managers for the offering. LifeSci Capital is acting as lead manager and H.C.

The activated neurohormones angiotensin II, aldosterone, and norepinephrine ... and therefore better diuretic delivery to the kidneys. Hence, supine positioning can increase the diuretic response ...

APAs are benign (non-cancerous) tumors that develop on the adrenal glands—small glands on top of the kidneys that produce important hormones, such as aldosterone, cortisol and sex hormones.

BofA Securities, Evercore ISI, Goldman Sachs & Co. LLC, Stifel and Wells Fargo Securities acted as joint book-running managers for the offering. LifeSci Capital acted as lead manager and H.C.