The androgen receptor is the primary driver of the initiation and growth of prostate cancer, the second-leading cause of death in men. Looking to have a better understanding of how the androgen ...

New androgen receptor structure suggests prostate cancer treatment options. Baylor College of Medicine. Journal Molecular Cell DOI 10.1016/j.molcel.2020.06.031 ...

Looking to have a better understanding of how the androgen receptor works in prostate cancer, researchers at Baylor College of Medicine conducted comprehensive studies of the 3-D structure of the ...

A large number of naturally occurring mutations of the human AR gene have provided important information about AR molecular structure and intermolecular interactions. AR is also a critical mediator of ...

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones ...

A research team has studied for the first time the 3-D structure of the homodimeric androgen receptor ligand-binding domain, a structure that eluded researchers for years. This new structure of ...

Prostate cancer is one of the most common malignancies in men globally. Hormonal therapies targeting the androgen–androgen receptor axis have significantly delayed disease progression. However, drug ...

Scale bar in τ-STED inset: 300 nm [Max Planck Institute for Molecular Genetics] “We modified the chemical features of the compound to match the features of androgen receptor condensation ...

Looking to have a better understanding of how the androgen receptor works in cancer, researchers at Baylor College of Medicine conducted comprehensive studies of the 3-D structure of the receptor.