In a scientific first, researchers from Vanderbilt University and the University of California, San Diego, have generated a ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, ...

EEST Darolutamide receives EU approval in third indication for patients with advanced prostate cancer European Commission granted approval ...

Researchers have solved a mystery that has confounded scientists for 80 years: the crystal structure of the ...

Prostate cancer is one of the most common malignancies in men globally. Hormonal therapies targeting the androgen–androgen receptor axis have significantly delayed disease progression. However, drug ...

The structure showed 12 transmembrane helices in two pseudo-symmetric bundles and two periplasmic subdomains. Experiments showed that the coiled-coil domain, whose predicted model extends from one of ...

E ver clean clumps of hair out of your shower drain and find yourself wondering how much hair loss is normal? Though it can be alarming to see an uptick in shedding, there's usual ...

Overall, this study sheds light on the intricate ways in which androgens contribute to sex differences at the cellular and molecular levels and provides the foundation for developing targeted ...

"We modified the chemical features of the compound to match the features of androgen receptor condensation, resulting in a tenfold increase in the potency of the molecule in castration-resistant ...