The three main types of granulocytes are neutrophils, eosinophils and basophils. Sexual dimorphism is a feature of many cancers, but how this functions is often unclear. Here the authors show that ...

These include the accumulation of potentially beneficial IgE–anti-IgE immune complexes and the downregulation of the high-affinity IgE Fc receptors (FcɛRI) on basophils and mast cells.