p53 levels were quantified using total p53 assay kit [K150DBA-3 ... KT-253 leads to potent p53 stabilization and induction of apoptosis To investigate the effect of KT-253 treatment on cell cycle ...

Ovarian cancer, a leading cause of death among gynecological malignancies, has a poor prognosis and low 5-year survival rate, necessitating new therapeutic strategies. CDK4/6 inhibitors show promise ...

This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

Figure 5A shows the wound healing assay results. The migration rate of A549 ... augmented the inhibitory effects of radiation by inducing apoptosis, causing G2/M phase cell cycle arrest, inhibiting ...

B-cell acute lymphoblastic leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common childhood cancer, making up 35% of pediatric cancer cases ...

In this webinar brought to you by Lonza, Ethan Shelkey and Aurita Menezes will discuss the effects of donor variability in cell-based assays for measuring drug immunogenicity and immunotoxicity. Lab ...

We used human bladder cancer T24 cell as the target cell, and assessed the effects of GA on T24 cells proliferation, apoptosis, cell cycle distribution ... For cell counting kit-8 (CCK-8) assay, T24 ...

The observed long-range intra-generational correlations in cell-cycle duration, up to second cousins, seem paradoxical because ancestral correlations decay rapidly. However, this correlation pattern ...

In Ming-Chiu Fung’s immunology lab, Hogan had been investigating how disturbances in the cytoskeletons of cells might contribute to the fragmentation of mitochondria during apoptosis, the most ...