Petrenko V, Sinturel F, Riezman H, Dibner C. Lipid metabolism around the body clocks. Progress in lipid research ...

By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.

Get Instant Summarized Text (Gist) Neurons maintain their connections using simple physics, specifically through vesicle density, which acts like an invisible glue. In Alzheimer's disease, this ...

Scientists at Auburn University have uncovered a fundamental principle of how brain cells stay connected, and their discovery could change how we understand Alzheimer's disease. Published in Cell ...

Background: Presynaptic G i/o coupled GPCRs can act as negative feedback regulators of neurotransmitter release via Gβγ effector modulation through two mechanisms: decreased calcium influx and direct ...

Endothelial cells maintain the integrity of the vasculature. In response to injury, endothelial cells undergo exocytosis, releasing various compounds into the blood stream by vesicle fusion with the ...

State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, National Biomedical Imaging Center, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, College of Future ...

We analyze how interactions between GluA1 and 4.1N or SAP97 regulate IT and exocytosis in basal conditions and after cLTP induction. The down-regulation of 4.1N or SAP97 decreases GluA1 IT properties ...