Gout is a common inflammatory arthritis that has been increasing in both prevalence and incidence. Consequently, management of refractory and chronic gout has been gaining attention. Onset of gout is ...

This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and ...

Episode 8: Frequently asked questions about gout and uncontrolled gout Brian LaMoreaux, MD, MS, answers frequently asked questions, with topics including: how to define uncontrolled gout, how to ...

Sobi starts rolling application for refractory gout drug SEL-212 in the US, hoping to take on Amgen’s Krystexxa in the market.

For patients with gout who cannot get relief using standard therapies, daily life can be a painful, debilitating experience. Now, phase 3 results with a new drug from Sobi and Selecta suggests ...

Find out how you can change a circuit by adding items like switches with this Bitesiz KS2 science animation and a fun activity.

Gout can affect the ankle and other joints in the body, although the classic sign of this type of inflammatory arthritis is pain in the big toe. Gout occurs when uric acid builds up in the body and ...

Gout is the most common inflammatory arthritis and one in which pathogenesis and risk factors are best understood. One of the treatment objectives in current guidelines is ‘cure’. However, audits show ...

Background New drugs and new evidence concerning the use of established treatments have become available since the publication of the first European League Against Rheumatism (EULAR) recommendations ...