The histiocytes are small, monomorphous and exhibit an abundant cytoplasm, notably devoid of cytoplasmic lipid accumulation. Accompanying this infiltrate, there is an inflammatory component consisting ...

Langerhans cell histiocytosis is a rare hematologic disease characterized by the accumulation of histiocytes, which can lead to organ dysfunction.

Kikuchi-Fujimoto Disease: An Exuberant Localized T Cell Activation Arrested By Histiocytes?

Kikuchi-Fujimoto disease, or histiocytic necrotizing lymphadenitis, is a relatively new disease entity seen in the U.S. that primarily affects young women. By 1993 approximately 200 cases had been ...

HLH is an immune deficiency disorder which happens when certain types of white blood cells, known as histiocytes and lymphocytes, become overactive and attack the body.

What happened next: The surgeon had the lump removed, and an analysis revealed that it was a cancerous fibrous histiocytoma, a type of tumor containing histiocytes — immune cells that migrate ...

Biopsy showed intermixed xanthomatized histiocytes positive for CD163, and negative for factor XIIIa and BRAFV600E. A PET-CT scan showed mild fludeoxyglucose (18F)-avidity in bilateral lower leg ...

Langerhans cell histiocytosis comprises a heterogeneous range of clinical manifestations secondary to clonal proliferation of histiocytes, characterized by the accumulation of these cells in various ...

There are two main types of rare blood disorders: myeloproliferative and lymphoproliferative. Treatment depends on the type but can involve chemotherapy or stem cell transplants.

However, increased histiocytes, as well as bone marrow fibrosis, was associated with worse overall survival. Dr. Yeung explained that this potential contradiction with histiocytes may be due to the ...

If you have hemophagocytic lymphohistiocytosis, your immune system does not work normally. Certain white blood cells — histiocytes and lymphocytes — attack your other blood cells. These abnormal blood ...