Yes, I do think we need non-glucocorticoid forms of therapy to treat 21-hydroxylase deficiency congenital adrenal hyperplasia.The most common form of congenital adrenal hyperplasia (CAH) is a ...

Individuals with type 2 diabetes mellitus (DM) can have hypothalamic–pituitary–adrenal (HPA) axis dysfunction and cognitive impairment. Bruehl et al. sought to determine whether HPA ...

The hypothalamic-pituitary-adrenal (HPA) axis connects the hypothalamus to the anterior pituitary gland through the infundibulum. Capillaries within the infundibulum allow hormones released by the ...

Exclusion criteria included presence of a severe comorbidity, known disease of the hypothalamic-pituitary-adrenal axis, or use of drugs that interfere with cortisol metabolism or measurement.

Adrenal steroidogenesis is under the control of the hypothalamic–pituitary–adrenal (HPA) axis. Furthermore, metabolic factors including insulin and obesity-related signals may play a role in ...

Low-dose oral corticosteroids have been shown to have marginal and transient hypothalamic-pituitary-adrenal axis suppression if used for a short period (i.e. < 7 days). [7] Intranasal ...