The investigational compound SAP-001 had a sustained effect on serum urate levels vs placebo, but not on gout flares in a Phase 2b study.

Understanding how molecular arrangements within crystals influence their thermal behavior is a fundamental question in solid-state chemistry. This topic is especially relevant in pharmaceuticals ...

Gout patients who met a target serum urate level of < 360 μmol/L (6 mg/dL) within 12 months of treatment cut their risk for major cardiovascular events vs patients who did not.

Many viruses induce the formation of altered membrane structures upon replication in host cells. This Review examines how viruses modify intracellular membranes, highlights similarities between ...

Episode 8: Frequently asked questions about gout and uncontrolled gout Brian LaMoreaux, MD, MS, answers frequently asked questions, with topics including: how to define uncontrolled gout, how to ...