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Cheng et al. identify a mitochondrial complex IV (CIV) deficiency in the brains of patients with sporadic amyotrophic lateral sclerosis (ALS). They demonstrate that defects in mitochondrial CIV ...

Negative feedback control brings about changes that help return the body to normal conditions. If the body temperature drops, negative feedback control raises the temperature back to normal. If ...

The pituitary gland and hypothalamus in a healthy brain signal the release of endorphins during moments of shock, fear, trauma, stress, or physical pain. They can then bind to receptors in the nervous ...

We highlight the roles of subcortical regions (and their subunits) such as the bed nucleus of the stria terminalis, the amgydala, and the hippocampus, as well as their connectivity to cortical regions ...