Tertiary lymphoid structures (TLS) are increasingly recognized to have roles in cancer. Within tumor microenvironments (TME), TLS can arise as ectopic lymphoid organs containing aggregates of ...

Non-Hodgkin's lymphoma (NHL) occurs when lymphocytes called T cells and B cells become cancerous. Although there are many subtypes of lymphoma, skin lymphomas only make up about 4% of the total of all ...

Calcium plays an essential role in lymphocyte activation and maturation but the exact effect on gene expression is not known. In April Nature Immunology Stefan Feske and colleagues from Harvard ...

Lymphocytes are white blood cells that help the body fight infection and disease. The healthy range for an adult is between 1,000 and 4,800 lymphocytes per microliter (µL) of blood. Doctors will ...

A clinical team has spearheaded the use of CAR-T cell therapy for blood cancers. The researchers recently treated the first myeloma patient with this therapy, resulting in a very good response without ...

But let's back up and make this easier to understand. A lymphocyte is a type of white blood cell that has functions in the immune system to help protect the body from infection. The two main types are ...

What Is B-Cell Lymphoma? B-cell lymphoma is a cancer that forms in your white blood cells called lymphocytes. These cells are made by your lymphatic system, which plays an important role in immunity.

B-lymphocytes provide an excellent model to study these kinds ... and autophagy proteins impact expansion of these types of B cell population and affinity maturation of antibodies. These studies ...

Despite antigen affinity of B cells varying from cell to cell, functional analyses of antigen-reactive B cells on individual B cells are missing due to technical difficulties. Especially in the field ...