(A) Volcano plot of DEGs in monocytes/macrophages between NC and CRC samples in the GSE164552 dataset. (B) Venn diagrams of common ... integrates single-cell and spatial transcriptomics with ...

This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

Beyond its role in the initiation of digestion, the oral microbiome appears to be key to maintaining both oral and systemic ...

Interestingly, we found that H3K27ac at promoters is enriched for G-quadruplex DNA secondary structure-forming ... cytokines in stimulated cells suggesting the induction of a memory response by the ...

Objectives Proximal hamstring tendon avulsion injuries are severe and potentially career-threatening for elite athletes.

As a suitable platform for in vitro cell culture, microfluidic technology has attracted ... Methods ‘Gut-on-a-chip’ can be divided into three types based on its structure. The first type of ...

Neuroscientists have produced the largest wiring diagram and functional map of a mammalian brain to date using tissue from a ...

From a tiny sample of tissue no larger than a grain of sand, scientists have come within reach of a goal once thought ...

Researchers say they have mapped more than 200,000 cells in a cubic millimeter of brain tissue and have traced how they're all connected.

In this application note, explore how scientists can couple a serum-free medium with a xeno-free serum replacement to effectively culture functional monocyte-derived dendritic cells and macrophages.