The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

Figure 7 Schematic diagram of the major transcriptional regulation during the development of HSCs to monocytes. Most gene transcriptional expressions related to cell metabolisms, signal pathways, and ...

The recruitment of monocytes by activated ECs and their differentiation ... Inserts were then transferred into plates containing LPS stimulated adherent macrophage-like THP-1 cells. A diagram of this ...

Given the importance of thrombosis as the trigger for acute myocardial ischaemia, it is necessary to know something about the structure of plaques ... of cholesterol (foam cells). These macrophages ...

Atherosclerosis cardiovascular disease (ASCVD)-related mortality is higher in patients with lupus nephritis (LN) compared ...

Understanding the behavior of tiny droplets in our cells could aid the search for new treatments. A team of Leiden ...

A new version of Cellpose —the popular tool that maps the boundaries of diverse cells in microscopy images —now works on less-than-perfect pictures that are noisy, blurry, or undersampled.

When a tumor develops, it creates a structure around itself called the tumor stroma, within which blood and lymphatic vessels ...

But filopodia can also wreak havoc: metastatic cancer cells use them to invade new regions of the body. Filopodia are composed of hexagonal bundles of proteins that give them structure and strength.

A research team led by Prof. WENG Jianping from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) revealed that insulin-like growth factor-binding ...