A pioneering study offers unprecedented insights into the bone immune microenvironment of type 2 diabetic mice, uncovering a ...

Clinical research has long focused on ways to harness the actions of the immune system. From vaccines to immunotherapies, ...

Discover how protein intake, hormone balance, gut health, and exercise types work together with nutrients beyond calcium to ...

When we think of type 2 diabetes, images of heart problems or kidney damage often come to mind. But lurking quietly behind these well-known complications is another serious threat—bone disease.

Researchers have shown that innate immune training, also known as trained immunity (TRIM), leads to aggravated bone loss in experimental models of periodontitis and inflammatory arthritis.

A new study in Genes & Diseases has revealed that heavy mechanical force can decelerate orthodontic tooth movement (OTM) by ...

“We found that this treatment primed osteoclast precursors to differentiate into osteoclasts more readily if presented with an inflammatory challenge like arthritis,” says Chavakis. “So, although TRIM ...

Clinical research has long focused on ways to harness the actions of the immune system. From vaccines to immunotherapies, researchers have used their ...

(A) Monocytes and MΦ from all PTOA and RA immune cell datasets were computationally isolated, resulting in three clusters: MΦ, monocytes and osteoclast-like cells. (B) Feature plots showing expression ...