Our genes determine the size and shape of our skeleton, but our diet and lifestyle can help maintain healthy bones ...

Bone dynamics depend on two associated cell types: osteoblasts, which are responsible for bone formation, and osteoclasts, which are responsible for bone resorption. Until now, it has not been ...

First, despite its superficially inert appearance, bone is rapidly and continuously remodeled at a high rate by bone-forming osteoblasts and bone-resorbing osteoclasts. The latter differentiate ...

Reducing circulating estrogen levels increases osteoclast activity and, therefore, bone loss. 9 Not only is the balance of osteoblasts and osteoclasts altered, but the microenvironment of the ...

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts ...