This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing ...

New methods for deriving macrophages from induced pluripotent stem cells are easier to scale and provide more clinically ...

Modern cancer treatments have evolved beyond traditional chemotherapy to include targeted approaches such as immunotherapy, ...

Used clinically since the 1920s, corticosteroids interrupt multiple steps in immune activation because of the ubiquitous expression of corticosteroid receptors. Corticosteroids inhibit antigen ...