The receptor for advanced glycation end products (RAGE) has been demonstrated to play a central role in pathogenic mechanisms of a growing number of important neurological and other diseases ...

HMGB-1, sRAGE and RAGE have been involved in sepsis and their potential as severity markers has been proposed. The aim of this study was to evaluate HMGB-1, RAGE and sRAGE levels in patients with ...

Strategies that aim to neutralize DAMPs or their receptors have proven effective in murine models. On the other hand, intracellular signaling cascades activated by TLRs or RAGE might be attractive ...