Reduced receptor-mediated LDL endocytosis causing raised blood LDL cholesterol (LDL-C) is the main defect, but other abnormalities due to lack of LDL receptors include altered hepatic cholesterol ...

Clathrin-mediated endocytosis is a major endocytic route ... For example, uncontrolled cell growth caused by defects in receptor internalization might be corrected by specifically stimulating ...

Learn how nanoparticles cross the blood-brain barrier (BBB) and explore their potential in treating neurological disorders ...

After internalization by receptor-mediated endocytosis, the cleaved diphtheria toxin kills the cell by interfering with cellular protein synthesis via ADP ribosylation of elongation factor-2.

Extracellular vesicles are membrane-bound particles released by cells that serve as crucial mediators of intercellular communication, carrying proteins, lipids, and nucleic acids. Their ...

Fortunately, the body has a rescue team at the ready. It consists of the blood protein haptoglobin, which binds to and ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

A new Drosophila collection of Parkinsonism models reveals early synaptic cholinergic projection neuron dysfunction, linking synaptic failure to later dopaminergic decline, highlighting a role for ...

Background Development of diffuse-type gastric cancer (DGC) starts with intramucosal lesions that are primarily composed of ...

Earlier this week, Cuba completed the release of 553 prisoners despite the collapse of a deal with the United States, Vatican News reported. In January, under the Catholic Church’s mediation ...