The newborn mouse is relatively immuno-incompetent and potentially susceptible to tolerance to allogeneic cells. As a prelude to assessing the effects of monoclonal antibody (MoAb) on newborn ...

Cytotoxic T lymphocytes and natural killer cells are essential effectors of ... with the YTS 169 monoclonal antibody used for in vivo depletion. Fisher's exact method was used to interpret the ...

MONT-SAINT-GUIBERT, Belgium, March 17, 2025 (GLOBE NEWSWIRE) -- EsoBiotec SA, a biotechnology company pioneering in vivo cell therapies that has demonstrated promising early clinical activity ...

That trial, the first randomized, double-blind, placebo-controlled study ever conducted in IgG4-RD, confirmed “beyond doubt” that B-cell depletion ... harmful T cells and by directly secreting ...

expect to report clinical data from both studies in 2025 Presented preclinical data in non-human primates showing safety and deep B cell depletion using a surrogate for SG299, an in vivo CAR T ...

ENaBL uses highly targeted lentiviruses to deliver genetic instructions to specific immune cells, such as T cells ... cell depletion, typically taking weeks. By engineering immune cells directly ...