This important study shows that the Nora virus, a natural Drosophila pathogen that also persistently infects many laboratory fly stocks, infects intestinal stem cells (ISCs), leading to a shorter life ...

Two oral presentations will highlight the continued potent antiviral activity of ALG-000184 for chronic hepatitis B virus (HBV ... Monotherapy with the Capsid Assembly Modulator ALG-000184 ...

The isolate from sample 85 had a single morphotype of approximately 200 nm in size, displaying an icosahedral shape ... capsid proteins, as well as the membrane composition. These factors not only ...

The firm said this view is based on encouraging efficacy to date, the use of a different adeno-associated virus capsid and transgene versus Elevidys, and a clean safety profile to date ...

“I thought, ‘What can I do for the next 20 or 30 years?’” He found an answer in SARS-CoV-2, the virus responsible for the COVID-19 pandemic, that was rapidly spreading around the worl ...

Unlike traditional antiretrovirals that target enzymes such as reverse transcriptase or protease, LEN binds directly to the capsid protein, disrupting several critical steps in the virus’s life ...

“I thought, ‘What can I do for the next 20 or 30 years?’” He found an answer in SARS-CoV-2, the virus responsible for the COVID-19 pandemic, that was rapidly spreading around the worl ...

Lenacapavir is the only approved HIV capsid inhibitor. Teropavimab (GS-5423) is derived from a bnAb called 3BNC117 that targets the CD4 binding site, which the virus uses to enter cells. Zinlirvimab ...