"Randomized controlled trials are pretty much the gold standard, but they’re not always ethical," said Mary Kathryn Grabowski, an assistant professor in epidemiology at Johns Hopkins University.

The primary efficacy outcome among the 550 participants with initially uncontrolled asthma showed significantly better ...

Mean Reversion in Randomized Controlled Trials: Implications for Program Targeting and Heterogeneous Treatment Effects, AEA Papers and Proceedings, 115, (221-225), ...

Fabricatore, AN, Wadden, TA, Moore, RH, et al. Attrition from randomized controlled trials of pharmacological weight loss agents: a systematic review and analysis. Obes Rev 2009;10:333-341.

Patients with skin cancer who were fed a high-fiber diet showed better response rates to treatment and longer event-free ...

In a first of its kind randomised controlled trial, researchers found delivering a problem solving digital mental health intervention to young Ukrainian refugees significantly reduced symptoms of ...

A low-emulsifier-containing diet led to a threefold increased likelihood of improvement in symptoms of Crohn’s disease ...

Critics will argue that double-blind placebo-controlled trials provide more reliable information than real-world clinical ...

Both randomized controlled trials and real-world evidence can help define a treatment’s absolute value and its value relative to alternative interventions, but they do so in different ways.