eLife22h
Inference technique for the synaptic conductances in rhythmically active networks and application to respiratory central pattern generation circuits
Unraveling synaptic interactions between excitatory and inhibitory interneurons within rhythmic neural circuits, such as central pattern generation (CPG) circuits for rh ...
eLife22h
Information gain at the onset of habituation to repeated stimuli
This manuscript presents a valuable minimal model of habituation which is quantified by information theoretic measures. The results here could be of use in interpreting habituation behavior in a range ...
eLife22h
Being Neurodivergent in Academia: Navigating neurodiversity in higher education in India
True inclusion starts in academia when we move from a deficit-based perspective to one that recognises and nurtures the unique strengths and talents of neurodivergent individuals.
eLife22h
Stem Cells: Don’t be so naïve
However, how mechanical signals regulate naïve pluripotency is not well understood. Mechanical signals are relayed in part through cellular adhesions that anchor cells to each other and to their ...
eLife1d
Bacteriophage infection drives loss of β-lactam resistance in methicillin-resistant Staphylococcus aureus
The manuscript explores how bacterial evolution in the presence of lytic phages modulates b-lactams resistance and virulence properties in methicillin-resistant Staphylococcus aureus (MRSA). The work ...
eLife1d
Emergence of planar cell polarity from the interplay of local interactions and global gradients
Planar cell polarity (PCP) – tissue-scale alignment of the direction of asymmetric localization of proteins at the cell-cell interface – is essential for embryonic development and physiological ...
eLife2d
A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit
This important work attempts to establish a causal link between neurotrophin signaling and experience-induced structural plasticity in dopaminergic circuits in the adult fly brain, a topic of broad ...
eLife1d
Update on eLife’s indexing status at Web of Science
Following Web of Science’s decision to place eLife “on hold” while it reevaluates our review process, we explain what this means for authors and outline our next steps.
eLife2d
Becker muscular dystrophy mice showed site-specific decay of type IIa fibers with capillary change in skeletal muscle
The authors present three valuable transgenic models carrying three representative exon deletions of the dystrophin gene. The findings are supported by rigorous biochemical assays and state-of-the-art ...
eLife4d
Aberration correction in long GRIN lens-based microendoscopes for extended field-of-view two-photon imaging in deep brain regions
Two-photon (2P) fluorescence imaging through gradient index (GRIN) lens-based endoscopes is fundamental to investigate the functional properties of neural populations in deep brain circuits. However, ...
eLife4d
Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single cell RNA sequencing
Endocrine Neoplasia Translational Research Center, Division of Endocrinology, Diabetes and Metabolism, Chaim Sheba Medical Center, and Tel Aviv University Faculty of Medicine, Ramat Gan, Israel This ...
eLife3d
Membrane potential modulates ERK activity and cell proliferation
Department of Physiology, Division of Life Science, Faculty of Medicine, Osaka Medical and Pharmaceutical University, Takatsuki, Japan ...