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When Alois Alzheimer described the case of Auguste D. to an audience of fellow psychiatrists in Tuebingen, Germany, in 1906, what set her case apart was the fact that her dementia appeared before she ...

What goes wrong first in the Alzheimer’s disease brain? Scientists led by Marc Aurel Busche of the U.K. Dementia Research Institute at University College London may have an answer. In the May 7 Neuron ...

This interactive resource organizes decades of data on biomarkers for Alzheimer's disease. Biomarker measurements from the cerebrospinal fluid and blood are curated from the primary literature and ...

Atherosclerotic arteries aren’t just a problem for the heart—they’re bad news for the brain, too. Now, scientists led by Wei Wang, Dai-Shi Tian, and Chuan Qin of Huazhong University of Science and ...

Now that doctors are prescribing anti-amyloid therapies for Alzheimer’s disease, scientists have begun to focus their energy on the other pathological hallmark of AD, neurofibrillary tangles. While ...

Creating models for primary tauopathies sounds simple enough. Select a human tau gene variant that causes disease, stick it where the endogenous mouse gene sits in its genome, then wait a few months ...

From April 24-25, the Tau Global Conference, a.k.a. Tau2025, drew 600 people to a hotel in Hyde Park, London, with 500 more following the science online. Attendance well surpassed Tau2020, the first, ...

Neurofibrillary tangles mark Alzheimer’s disease and a plethora of primary tauopathies. How best to study them in the lab? Most mouse tauopathy models overexpress the human tau protein and are highly ...

In a milestone for Alzheimer’s disease diagnosis and care, the U.S. Food and Drug Administration on May 16 cleared for marketing the first AD blood test. Fujirebio’s Lumipulse G p-tau217/Aβ42 ...

As awareness about dementia continues to grow worldwide, a spate of online courses aims to help both health professionals and the general public understand Alzheimer’s and related diseases. Below is a ...