Blincyto ® (blinatumomab), manufactured by Amgen, is a bispecific CD19-directed CD3 T-cell engager. It is approved by the US Food and Drug Administration (FDA) for the treatment of adults and children ...

Between baseline and week 52, spinal canal dimensions numerically improved with navepegritide compared to placebo across L1 to L5. Weekly administration of navepegritide led to improvements in overall ...

The study will assess the number and severity of dose-limiting toxicities and adverse events. A new study will evaluate the safety and efficacy of universal allogeneic anti-CD19/BCMA CAR T-cells in ...

Questions remain regarding the exact relationship between AAV and inflammatory bowel diseases. A young adult female patient with a history of ulcerative colitis was subsequently diagnosed with ...

In patients who had undergone limb lengthening surgery, the annual growth velocity increased from 2.2 ± 0.7 to 6.5 ± 0.7 centimeters per year. Vosoritide significantly increased annual growth velocity ...

The findings from this study highlight the importance of further investigation of nailfold videocapillaroscopy when evaluating of patients with AAV in different age groups. In children with ...

For the last 3 years, the PBC Foundation, based in Edinburgh, Scotland, has conducted an annual summit that addresses the challenges and potential remedies for those living with primary biliary ...

The primary outcome measures include assessing I-RODS scores at baseline and monitoring variations at 6 and 12 months after enrollment An upcoming observational, noninterventional study aims to assess ...

Stiripentol appears to be a tolerable and effective treatment for seizures in patients with Dravet syndrome (DS) and other similar conditions, according to a study published in the journal Neurology ...

A type I mutation in the CALR gene led to the downregulation of basal mTOR complex 2 (mTORC2) signaling without having an effect on mTORC1 signaling. Using a cell culture approach, a team of ...

Patients with a history of myeloproliferative syndrome should be highly alert to the possibility of BCS in the presence of abdominal pain, ascites, and hepatomegaly. Polycythemia vera (PV) can ...

Elevations in AFP-L3 and ALT concentrations, despite low AFP levels, support the need to use a multi-marker panel to strengthen the accuracy of HCC diagnoses. In patients with hepatocellular carcinoma ...