eLife1d
Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly Parkinsonism models
A new Drosophila collection of Parkinsonism models reveals early synaptic cholinergic projection neuron dysfunction, linking synaptic failure to later dopaminergic decline, highlighting a role for ...
EMBO Press3d
Dimerization of GAS2 mediates crosslinking of microtubules and F-actin
GAS2 is a cytoskeletal regulator that interacts with both F-actin and microtubules. Here, cryo-EM structures of GAS2 domains ...
Android4d
AH Real Deal: Samsung's Galaxy Tab A9+ is now 27% off
Samsung’s Galaxy Tab A9+ is currently on sale, and if you’re looking for a good deal on a tablet, this is definitely worth taking a look at. Normally, the Galaxy Tab A9+ would cost you $219.99 ...
AHA/ASA Journals3d
Lymphatic Endothelial Branched-Chain Amino Acid Catabolic Defects Undermine Cardiac Lymphatic Integrity and Drive HFpEF
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, but ...
ahajournals.org6d
Choroidal Neovascularization Is Suppressed With Activation of TREM2 in Mononuclear Phagocytes
Mononuclear phagocytes contribute to pathological angiogenesis in age-related macular degeneration, a leading worldwide cause of visual impairment. However, the mechanisms that orchestrate the ...