These include the accumulation of potentially beneficial IgE–anti-IgE immune complexes and the downregulation of the high-affinity IgE Fc receptors (FcɛRI) on basophils and mast cells.

The three main types of granulocytes are neutrophils, eosinophils and basophils. Sexual dimorphism is a feature of many cancers, but how this functions is often unclear. Here the authors show that ...

The basophil activation test (BAT) is a diagnostic tool for cefuroxime-induced immediate-type reactions, whereas the lymphocyte transformation test (LTT) is typically applied in delayed-type drug ...

High neutrophils and low neutrophils can be caused by certain health conditions, medications, or medical treatments. Called neutrophilia, high neutrophils can mean you have an acute infection or ...

The basophil activation test (BAT) is not a primary diagnostic tool; it is a test complementary to the skin test and quantification of allergen-specific IgE. The BAT is currently mostly applied in ...

C. Ohnmacht et al., “Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths,” Immunity, 33:364-74, 2010. Free F1000 Evaluation Basophils were deemed critical in ...

Finally, granulocytes have not been much studied in swine blood. Indeed, the use of PBMCs in many studies may bias results due to the loss of particular populations (i.e., granulocytes) during cell ...