For example, Atchison et al. generated a tissue-engineered vascular model of Hutchinson-Gilford progeria syndrome (184). Moreover, modeling vascular diseases using hPSCs extends to complex disorders ...

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and FACT activity and nucleosome disassembly and assembly that allows us to propose a global model for the role of H2B ubiquitination in chromatin dynamics (Figure 7). Ubiquitination of H2B by ...