For example, researchers will measure cell death to determine a drug’s anticancer effectiveness. Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark ...

are frequently used as apoptosis assays in vivo. Mitochondrial apoptotic signalling and mitochondrial outer-membrane permeabilization (MOMP) controlled by the B-cell lymphoma 2 (BCL-2) family of ...

Ovarian cancer, a leading cause of death among gynecological malignancies, has a poor prognosis and low 5-year survival rate, necessitating new therapeutic strategies. CDK4/6 inhibitors show promise ...

In Ming-Chiu Fung’s immunology lab, Hogan had been investigating how disturbances in the cytoskeletons of cells might contribute to the fragmentation of mitochondria during apoptosis, the most ...

Moreover, the researchers analyzed the effects of miR-377 on apoptosis, proliferation, cell cycle ... as confirmed by luciferase assay and Real-time PCR. They observed a significant reduction ...

It expands assay capabilities to established and emerging markets such as cell and gene therapy, drug discovery, pathway analysis, cell counting, viability, apoptosis, cellular stress and immune ...

This study aimed to elucidate the molecular mechanism of TNIP1 regulation in the proliferation and apoptosis of breast cancer cells. A colony formation assay was conducted on MCF-7 and T47D cells ...