A new study from Auburn University provides new insights into neuronal connections, offering hope for the treatment of Alzheimer’s disease. Scientists at Auburn University have discovered a key ...

More information: Presynaptic recycling pool density regulates spontaneous synaptic vesicle exocytosis rate and is upregulated in the presence of beta-amyloid, Cell Reports (2025). DOI ...

This study reports that activation of TFEB promotes lysosomal exocytosis and clearance of cholesterol from lysosomes, the strength of evidence for which is convincing with appropriate and validated ...

Background: Presynaptic G i/o coupled GPCRs can act as negative feedback regulators of neurotransmitter release via Gβγ effector modulation through two mechanisms: decreased calcium influx and direct ...

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Get Instant Summarized Text (Gist) Neurons maintain their connections using simple physics, specifically through vesicle density, which acts like an invisible glue. In Alzheimer's disease, this ...

AUBURN, AL – Scientists at Auburn University have uncovered a fundamental principle of how brain cells stay connected, and their discovery could change how we understand Alzheimer’s disease.

Petrenko V, Sinturel F, Riezman H, Dibner C. Lipid metabolism around the body clocks. Progress in lipid research ...

College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China Hubei Province Key Laboratory of Biotechnology of Chinese Traditional Medicine, College of Health Science and ...