By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.

Background: Presynaptic G i/o coupled GPCRs can act as negative feedback regulators of neurotransmitter release via Gβγ effector modulation through two mechanisms: decreased calcium influx and direct ...

Endothelial cells maintain the integrity of the vasculature. In response to injury, endothelial cells undergo exocytosis, releasing various compounds into the blood stream by vesicle fusion with the ...