Nervous system dysregulation impacts health, linking stress responses to mental and physical conditions. Understand its ...

In recent years, the conversation around climate change has intensified, and for good reason. One driving factor in this ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

Conclusion: The IL6/ADPN/HMGB1 loop between adipocytes and macrophages in the border zone contributes to different clinical outcomes post-infarction. Thus, targeting the IL6/ADPN/HMGB1 loop may be a ...

Are the forest fires in California and the wildfires in Greece contributing to global warming? Could an increase in wildfires also increase the chances of more fires happening in the future?

Furthermore, we demonstrated that SENP1 is a direct target of HIF-1/2α and a previously unrecognised positive feedback loop exists between SENP1 and HIF-1α. Conclusions Taken together, our findings ...

But feedback control encompasses many feedback loops with diverse characteristics such as the brain regions involved and their response time. Which specific loops drive these performance improvements ...