In a randomized, crossover clinical trial in healthy young adults with varying weights, sucralose increased hypothalamic blood flow and its functional connections with brain regions involved in ...

“Body temperature regulation is primarily controlled by the hypothalamus, a region of the brain that acts ... Significant deviations from the average temperature can impair enzyme function, leading to ...

Neuronal deficiency of LGR4 improves hypothalamic leptin sensitivity via suppression of β- catenin signaling, which subsequently increases energy expenditure and decreases food intake, thus rendering ...

This important study identifies species- and sex-specific neuronal cell types and gene expression in the preoptic area (POA) to help understand the evolutionary divergence of social behaviors. The ...

What are the specific mechanisms by which stress affects energy metabolism and reproductive function? Studies showed that central mechanism, especially the hypothalamus, might be involved (6).

Cocaine- and amphetamine-regulated transcript (CART) is widely expressed in the hypothalamus and an important regulator ... highlighting the complex and nuclei-specific functions of CART in ...

(2) What are the effects of aging and lifestyle choices on physical activity? (3) What are the effects of aging on hypothalamic function and the orexin peptides? Discussion of these questions will ...