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Effects of monosodium urate crystals on intracellular JNK and ERK activities in FLS. Normal or RA-FLS were incubated with monosodium urate crystals (200 µg/ml) for 0–60 min.
WASHINGTON — Different stages of gout treatment may call for different serum urate targets, with certain levels being better for dissolving or preventing monosodium urate crystals, according to ...
Now A*STAR researchers have identified how the build-up of monosodium urate (MSU) crystals in the joints triggers such excruciating pain, raising the prospect of new treatments.
Abstract and Introduction Abstract. Monosodium urate crystals dissolve and are eliminated from joints and soft tissues as serum uric acid levels drop below its saturating point (400 μmol/l).
"We identified monosodium urate crystals by histology, electron microscopy, and negative birefringence on exposure of a frozen myocardial sample to polarized light," Frustaci's team said.
Monosodium urate (MSU) crystal deposits correlate with the degree of bone erosion displayed on dual-energy computed tomography (DECT), which may identify gout progression and joint damage earlier.
Ultrasound features of monosodium urate (MSU) crystal deposition in index joints at baseline were predictive of future gout flares in the same joints among patients initiating urate-lowering ...
“In the mouse models, they are seeing that even if you did not have a high level of uric acid, but you are seeing damage because of those tiny little, you know, monosodium urate crystals ...
New research shows that a high-fiber diet likely inhibits gout-related inflammation caused by monosodium urate (MSU) crystals. Skip to main content. Your source for the latest research news.
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