The study suggests alterations in a brain region called the hypothalamus, which are seen in early disease ... slowed disease progression in certain people with amyotrophic lateral sclerosis (ALS), ...

Central hypothyroidism is a rare disorder that occurs when an otherwise healthy thyroid doesn't produce enough hormones due to problems that originate in the pituitary gland, the hypothalamus, or both ...

No other causative genes were identified. This is the first report to demonstrate metabolic abnormalities and hypothalamic atrophy in a patient with a TBK1 mutation. Given that these abnormalities are ...

No matter what you've heard, you don't love anything with all of your heart. You love from the depths of your ventral tegmental area, your hypothalamus, your nucleus accumbens, and other vital areas ...

Catabolic neuronal pathways are those that both reduce food intake and increase energy expenditure (e.g., melanocortin neurons in the hypothalamic arcuate nucleus) and are stimulated by input from ...

dorsal raphe (DR), medial habenula (MHb), lateral habenula (LHb), paraventricular nucleus of the hypothalamus (PVH), extended amygdala (EAM), lateral hypothalamus (LH), and septum (cluster 3). These ...

The lateral preoptic area (LPO) is a hypothalamic region whose function has been largely unexplored. Its direct and indirect projections to the ventral tegmental area (VTA) suggest that the LPO could ...

Here, we show that depolarization of mouse arcuate nucleus (Arc) CART neurons via DREADD technology decreases energy expenditure and physical activity, while it exerts the opposite effects in CART ...

Additional results show that the lateral hypothalamus (LHA) is a critical downstream substrate for vHP ghrelin-mediated hyperphagia and that vHP ghrelin activated neurons communicate directly with ...