A clinical team has spearheaded the use of CAR-T cell therapy for blood cancers. The researchers recently treated the first ...

Chronic inflammation is involved in the development of abdominal aortic aneurysm (AAA). A tertiary lymphoid structure (TLS) within vascular lesions has recently been focused on for its role in ...

THE variability in the natural history of both acquired and idiopathic aplastic anemia makes it difficult to evaluate the success of any specific program of therapy. With careful attention to ...

Table 1 Human chemokines and chemokine receptors in lymphocyte traffic: a functional classification into inflammatory (pale green) and homeostatic (dark green) chemokines. Chemokines belonging to ...

Lymphocyte-activation gene 3 (LAG-3) has emerged as a key immune checkpoint regulating immune responses in the context of cancer. The inhibitory effect of LAG-3-expressing T cells contributes to ...

In conclusion, Tim-3 was characterized as a novel immune checkpoint molecule with pathophysiological significance in respiratory oncology. Its stage-dependent expression dynamics and multimodal ...

We generated induced excitatory neurons (iNeurons, iNs) from chimpanzee, bonobo, and human stem cells by expressing the transcription factor neurogenin-2 (NGN2). Single-cell RNA sequencing showed that ...

Human breast milk (HM) is the physiological nutrition during an infants' first few months of life, a crucial period for immune system development, metabolic and endocrine programming for growth, ...