A historic, old-fashioned general store near the Texas-Louisiana border is one of the best places for a pit stop in the southern part of the country.

A historic, old-fashioned general store near the Texas-Louisiana border is one of the best places for a pit stop in the southern part of the country. Jefferson General Store, located in Jefferson ...

Here’s which Florida country store ranked in WorldAtlas’s top five best general stores in the south and where it’s at in the state.

WorldAtlas says this family-run small business dating back more than 50 years is the best old-timey store in Georgia and among the South's top 5.

WorldAtlas says this family-run small business dating back more than 50 years is the best old-timey store in Georgia and among the South's top 5.

MEMPHIS, Tenn. - People in Northaven have what they like to call "a store to call their own," but it’s in need of a new owner. The Shelby Forest General Store opened in North Shelby County 91 ...

In Sagaponack, a newly revived general store is a blockbuster and a destination. A dozen miles away, it’s a very different story. How hard is it to open a cute little general store in the Hamptons?

At the front entrance of Hog Island Oyster Farm and the Boat Oyster Bar in Marshall, the former Marshall Post Office and Marshall Store, originally built by early settlers and residents Charlie and… ...

A wedding at their hometown's general store suited Katie and Steve's 15-year romance to a T.

Sarepta Therapeutics faces an "arduous path” to try to get its gene therapy for Duchenne muscular dystrophy back onto the market, a senior FDA official told STAT.

Jeff Vierstra was likely doomed by his DNA. A radical experiment gave him a chance to rewrite his fate — before ALS symptoms ever began.

Here’s which Florida country store ranked in WorldAtlas’s top five best general stores in the south and where it’s at in the state.