Neuromesodermal Progenitors (NMPs): Bipotent embryonic cells capable of differentiating into both neural and mesodermal tissues, playing a crucial role in axial elongation.

We highlight recent advancements and summarise various differentiation protocols, primarily utilising the Wnt signalling pathway agonist CHIR99021 and basic fibroblast growth factor (bFGF) to induce ...

Finally, in chick neuromesodermal progenitors, high glycolytic activity or elevated pHi promotes the non-enzymatic acetylation of β-catenin, which promotes mesodermal at the expense of neural cell ...

Secretory progenitors accumulated αKG, exhibited reduced expression of downstream TCA-cycle enzymes, and showed elevated DNA hydroxymethylation at loci associated with secretory fate.

Comparing the Switch 2 to the original Switch, Steam Deck, PlayStation 5, Xbox Series X, and a bunch of other gaming things — like old GamePros.

An immodest heap of succulent local lobster meat just barely dressed in mayo is the star of the dish, of course. But visually speaking, what helps make a lobster roll truly iconic is the split-top ...

Abstract We0086: Transcriptomic Profiling Links Senescent Fibro-Adipogenic Progenitors to Amputation and Mortality in Human Chronic Limb Threatening Ischemia Patients Hana Shafique, BS, Yueyuan Xu, ...

Dopaminergic neurons in the ventral midbrain are critical for regulating movement, cognition, and emotion. Ventral midbrain organoids can be used to model both development and diseases of the ...

We crossed Chmp5fl/fl mice with the line of Prrx1 -Cre [17], Col2 -Cre [18] or Osx -Cre [19] mice to delete the Chmp5 gene in Prrx1 -expressing limb mesenchymal progenitors (Chmp5Prrx1 mice), Col2 ...

Objectives Endothelial progenitor cells (EPCs) circulate with increased numbers in the peripheral blood of patients with highly-vascularised hepatocellular carcinoma (HCC) and contribute to ...

Age-Dependent Integration of Cortical Progenitors Transplanted at CSF-Neurogenic Niche Interface Provisionally accepted Gretchen Greene 1* Nikorn Pothayee 1* Jahandar Jahanipour 1 Hyesoo Jie 1 ...