New methods for deriving macrophages from induced pluripotent stem cells are easier to scale and provide more clinically ...

Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing ...

This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

FAMU-FSU College of Engineering researchers have created a new method for studying protein degradation within immune cells ...

Phagocytosis is a fundamental mechanism used by the body to resist pathogens and restore physiological homeostasis. Herein, to identify small molecules with anti-inflammatory properties via ...

School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China Engineering Research Center of Bio-Process, Ministry of Education, Hefei University of Technology, Hefei ...

Protective borders between the brain and the blood weaken with age. This includes the barrier formed by tightly linked epithelial cells in the choroid plexus, which generates cerebrospinal fluid. In ...

These particles can adhere to lung tissue, and macrophages—the white blood cells responsible for cleaning up such intruders—are tasked with removing them.

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components of the internal immune cells, which profoundly affects the internal ...

A research team has elucidated the mechanism behind bacterial cancer therapy using a genetically engineered bacterial strain. Their findings were published in Cell. Exploring the use of antitumor ...